Bipolar disorder, cognitive functioning and hypothalamic-pituitary-thyroid axis

Authors

  • C.M. Bonnin Bipolar Disorders Program Instituto de Neurociencias Hospital Clínico Universidad de Barcelona IDIBAPS Barcelona. Spain
  • A. Martinez-Aran Bipolar Disorders Program Instituto de Neurociencias Hospital Clínico Universidad de Barcelona IDIBAPS, CIBERSAM Barcelona. Spain
  • J. Sanchez-Moreno Bipolar Disorders Program Instituto de Neurociencias Hospital Clínico Universidad de Barcelona IDIBAPS Barcelona. Spain.；Psychiatry Department Universidad Autonoma de Madrid Madrid. Spain
  • C. Torrent Bipolar Disorders Program Instituto de Neurociencias Hospital Clínico Universidad de Barcelona IDIBAPS, CIBERSAM Barcelona. Spain
  • C. Franco Bipolar Disorders Program Instituto de Neurociencias Hospital Clínico Universidad de Barcelona IDIBAPS Barcelona. Spain
  • I. Pacchiarotti Bipolar Disorders Program Instituto de Neurociencias Hospital Clínico Universidad de Barcelona IDIBAPS, CIBERSAM Barcelona. Spain
  • Eduard Vieta Hospital Clínic Villarroel, 170 08036 Barcelona

Keywords:

Bipolar disorder, Hypothalamic-pituitary- thyroid axis, Neuropsychological functions

Abstract

The hypothalamic-pituitary- thyroid axis (HPT) in relation to bipolar disorder (BD) and neuropsychological functions has been studied little in the field of psychoneuroendocrinology. The aim of this study is to review the current status of the following subjects: (1) cognitive dysfunctions in BD as well as their hypothetic etiology; (2) response of the HPT axis in each phase of BD, and finally, (3) the connection between alterations in HPT and neuropsychological deficits.

After a careful analysis of the scientific literature, we conclude that more systematic research is needed because most of the issues, such as the role of HPT in BD and the implication of HPT in neuropsychological deficits, still remain unclear.

Downloads

Published

2010-07-01

How to Cite

Bonnin, C.M., et al. “Bipolar Disorder, Cognitive Functioning and Hypothalamic-Pituitary-Thyroid Axis”. Actas Españolas De Psiquiatría, vol. 38, no. 4, July 2010, pp. 223-8, https://actaspsiquiatria.es/index.php/actas/article/view/798.

Issue

Vol. 38 No. 4 (2010)

Section

Review